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  • Protein Degradation

    John Wiley & Sons. 2008. ISBN: 9783527620296,352762029X. 252 pages.

    The third of four volumes discusses the role of ubiquitin-mediated protein breakdown in cellular regulation and physiology. Required reading for molecular biologists, cell biologists and physiologists with an interest in the topic.

  • Protein Tyrosine Kinases

    Springer Science & Business Media. 2007. ISBN: 9781592599622,1592599621. 290 pages.

    Leading researchers, from the Novartis group that pioneered Gleevec/GlivecTM and around the world, comprehensively survey the state of the art in the drug discovery processes (bio- and chemoinformatics, structural biology, profiling, generation of resistance, etc.) aimed at generating PTK inhibitors for the treatment of various diseases, including cancer. Highlights include a discussion of the rationale and the progress made towards generating "selective" low molecular-weight kinase...

  • Protein Structure Prediction

    Springer Science & Business Media. 2018. ISBN: 9781592593682,1592593682. 422 pages.

    The deeper understanding of protein structure now emerging from cutting-edge research is not only illuminating evolutionary and biochemical mechanisms, but also promises enormous ramifications for molecular medicine, as well as for biotechnology, biophysics, biology, genetics, and other molecular sciences. In Protein Structure Prediction: Methods and Protocols, world-class investigators detail their most successful methods-and the theory behind them-for delineating the shape, form, and...

  • The G Protein-Coupled Receptors Handbook

    Springer Science & Business Media. 2008. ISBN: 1592599192,9781592599196. 412 pages.

    A comprehensive survey of the many recent advances in the field of G protein-coupled receptors (GPCR). The authors describe the current knowledge of GPCR receptor structure and function, the different mechanisms involved in the regulation of GPCR function, and the role of pharmacological chaperones in GPCR folding and maturation. They also present new findings about how GPCR dimerization/oligomerization modifies the properties of individual receptors and show how recent developments are...

  • Protein Structure

    CRC Press. 2003. ISBN: 0203911326,9780203911327. 576 pages.

    This text offers in-depth perspectives on every aspect of protein structure identification, assessment, characterization, and utilization, for a clear understanding of the diversity of protein shapes, variations in protein function, and structure-based drug design. The authors cover numerous high-throughput technologies as well as computational methods to study protein structures and residues. A valuable reference, this book reflects current trends in the effort to solve new structures...

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